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Username Post: Covid and Myocarditis        (Topic#24665)
penn nation 
Professor
Posts: 21086

Reg: 12-02-04
09-03-20 03:13 PM - Post#312772    

PSU doctor says 30%-35% of Big Ten athletes who tested positive for covid appeared to have myocarditis.

Should make all athletic conferences think twice:

https://www.centredaily.com/sports/college/penn-s t...

 
palestra38 
Professor
Posts: 32685

Reg: 11-21-04
Re: Covid and Myocarditis
09-03-20 03:18 PM - Post#312773    
    In response to penn nation

My obvious next question is what percentage of those testing negative have it?


 
penn nation 
Professor
Posts: 21086

Reg: 12-02-04
Re: Covid and Myocarditis
09-03-20 03:20 PM - Post#312774    
    In response to palestra38

Or, in general, what is the percentage of athletes say, a year ago, that had it?

It's hard to imagine that this would be an appreciable percentage.

I'm sure there's some baseline data somewhere that is being examined.

 
rbg 
Postdoc
Posts: 3044

Reg: 10-20-14
09-03-20 05:27 PM - Post#312780    
    In response to penn nation

Have non-athletes with covid been studied to find out if they have myocarditis in similar numbers?

 
rbg 
Postdoc
Posts: 3044

Reg: 10-20-14
03-04-21 01:08 PM - Post#321339    
    In response to rbg

Study shows less than 1% of pro athletes infected by COVID-19 also developed inflammatory heart disease

https://www.espn.com/espn/story/_/id/31003 626/stud...

- Five of 789 professional athletes infected with COVID-19 were later found to have suffered inflammatory heart disease in the largest study to date on the cardiac impact of the virus in sports.

In data published Thursday in JAMA Cardiology, doctors affiliated with six U.S.-based leagues followed the 789 infected players last year between May and October.

Before returning to play, the athletes underwent three noninvasive tests that tracked heart rhythms, took an ultrasound of their hearts, and measured a protein in their blood that can be a signal of heart damage. Thirty athletes had abnormal test results and were referred for a cardiac MRI. Doctors diagnosed five cases of inflammatory heart disease (0.6% of the total), including three cases identified as myocarditis and two as pericarditis.

Dr. David Engel, a cardiologist at the Columbia University Irving Medical Center and one of the paper's lead authors, said the results were in line with current assessments that cardiac injury from COVID-19 correlates with the severity of symptoms. The study incorporated infected athletes who were both symptomatic and asymptomatic. All five of the cases of cardiac illness included symptoms that "exceeded empirical definitions of mild COVID-19 illness," according to the paper. -

- The professional sports leagues who contributed data to the JAMA Cardiology paper -- the NBA, WNBA, NFL, NHL, Major League Baseball and Major League Soccer -- followed a standardized screening procedure recommended by the American College of Cardiology. It included blood tests, an electrocardiogram and a resting echocardiogram, or heart ultrasound. Further tests, and eventually diagnosis, were based on abnormalities from the initial screening.

"There was a lot of controversy about how to interpret these cardiac MRI studies and really what the meaning of these findings were," Engel said. "This study had a very clinically-relevant approach. Patients who tested positive went through the recommended screening from the American College of Cardiology. It was only after there were abnormalities that we went on for further testing. Using this step-wise approach, we found what we considered to be clinically-relevant incidents of myocarditis and pericarditis to be quite low." -

- The study did not shed light on what might happen over the long term with those players who were diagnosed with heart inflammation. They will continue to be monitored with MRIs to see if the effects fade away with time.

"Only time will tell if, five years from now, we'll have an epidemic of failed hearts," said Dr. Robert Bonow, a cardiologist at Northwestern University and editor of JAMA Cardiology, who was not affiliated with the study. "But I think that is unlikely."

Results of the two other forthcoming studies on the possible COVID-cardiac link are expected to be published soon, pending peer review. -

 
1LotteryPick1969 
Postdoc
Posts: 2262
1LotteryPick1969
Age: 73
Loc: Sandy, Utah
Reg: 11-21-04
03-10-21 09:41 AM - Post#321680    
    In response to rbg

Another study in JACC Imaging:

The investigators performed screening echocardiograms in 54 consecutive student athletes (mean age, 19 years; 85% male) who had positive results of reverse transcription polymerase chain reaction nasal swab testing of the upper respiratory tract or immunoglobulin G antibodies against severe acute respiratory syndrome coronavirus type 2. Sequential cardiac magnetic resonance imaging (CMR) was performed in 48 (89%) subjects. Comparisons of continuous variables of demographics, echocardiography, and CMR among different groups (i.e., control subjects, symptomatic COVID-19–positive student athletes, and asymptomatic COVID-19–positive student athletes) were performed using either the Kruskal-Wallis test with Dunn-Bonferroni correction or the Mann-Whitney U test.

Results:

A total of 16 (30%) athletes were asymptomatic, whereas 36 (66%) and two (4%) athletes reported mild and moderate COVID-19–related symptoms, respectively. For the 48 athletes completing both imaging studies, abnormal findings were identified in 27 (56.3%) individuals. This included 19 (39.5%) athletes with pericardial late enhancements with associated pericardial effusion. Of the individuals with pericardial enhancements, six (12.5%) had reduced global longitudinal strain and/or an increased native T1. One patient showed myocardial enhancement and reduced left ventricular ejection fraction or reduced global longitudinal strain with or without increased native T1 values was also identified in an additional seven (14.6%) individuals. Native T2 findings were normal in all subjects, and no specific imaging features of myocardial inflammation were identified. Hierarchical clustering of left ventricular regional strain identified three unique myopericardial phenotypes that showed significant association with the CMR findings (p = 0.03).

Conclusions:

The authors concluded that more than one in three previously healthy college athletes recovering from COVID-19 infection showed imaging features of a resolving pericardial inflammation.



 
Jeff2sf 
Postdoc
Posts: 4466

Reg: 11-22-04
03-10-21 11:28 AM - Post#321688    
    In response to 1LotteryPick1969

That's a big no for me, bud.

DUELING STUDIES? HOW FUN!

https://www.espn.com/espn/story/_/id/31003 626/stud...

 
PennFan10 
Postdoc
Posts: 3580

Reg: 02-15-15
03-10-21 01:07 PM - Post#321694    
    In response to Jeff2sf

And where is the study that links participation in sports (as opposed to any other activity a NARP would do) to any long term affects from Covid 19?

 
1LotteryPick1969 
Postdoc
Posts: 2262
1LotteryPick1969
Age: 73
Loc: Sandy, Utah
Reg: 11-21-04
03-11-21 02:39 PM - Post#321806    
    In response to PennFan10

I have not seen any studies looking at the heart of college age students post COVID who are not "athletes".

The concern of course is that competitive athletics AFTER infection might adversely affect the heart long term.

Or not. No one knows.

The disparate test results I think are largely due to screening with echo (less sensitive, more specific) and performing MRI only if echo abnormal, vs. performing MRI on everyone (very sensitive, less specific).

 
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